Algorithm, Analog Computing, Art, Automata, Bacteria, Biological Computation, Biology, Cybernetics, Deep Learning

Beyond design: cybernetics, biological computers and hylozoism (Pickering 2008)

Analog Computing, Bio hacking, Biological Computation, Biology, Biometrics, Brain, Cybernetics, DNA, Science

Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant

“Mammalian synthetic biology has significantly advanced the design of gene switches that are responsive to traceless cues such as light, gas and radio waves, complex gene circuits, including oscillators, cancer-killing gene classifiers and programmable biocomputers, as well as prosthetic gene networks that provide treatment strategies for gouty arthritis, diabetes and obesity. Akin to synthetic biology promoting prosthetic gene networks for the treatment of metabolic disorders, cybernetics advances the design of functional man–machine interfaces in which brain–computer interfaces (BCI) process brain waves to control electromechanical prostheses, such as bionic extremities and even wheel chairs. The advent of synthetic optogenetic devices that use power-controlled, light-adjustable therapeutic interventions18 will enable the merging of synthetic biology with cybernetics to allow brain waves to remotely control the transgene expression and cellular behaviour in a wireless manner.”


Algorithm, Analog Computing, Brain, Code, Cybernetics, Download, History, Interface, Logic, Mathematics, Memory

From Memex to Hypertext: Vannevar Bush and the Mind’s Machine (1991)

“Vannevar Bush, the engineer who designed the world’s most powerful analog computer, envisioned the development of a new kind of computing machine he called Memex. For many computer and information scientists, Bush’s Memex has been the prototype for a machine to help people think. This volume, which the editors have divided into sections on the creation, extension, and legacy of the Memex, combines seven essays by Bush with eleven others by others that set his ideas within a variety of contexts. The essays by Bush range chronologically from the early “The Inscrutable Thirties” (1933), “Memorandum Regarding Memex” (1941), and “As We May Think” (1945), to “Memex II” (1959), “Science Pauses” (1967), “Memex Revisited” (1967), and a passage from “Of Inventions and Inventors” (1970). Bush’s essays are surrounded by four chapters that place his changing plans for the Memex within his career and within information technology before digital computing. The contributors include Larry Owens, Colin Burke, Douglas C. Engelbart, Theodor H. Nelson, Linda C. Smith, Norman Meyrowitz, Tim Oren, Gregory Crane, and Randall H. Trigg.”

Memex animation