Analog Computing, Bio hacking, Biological Computation, Biology, Biometrics, Brain, Cybernetics, DNA, Science

Mind-controlled transgene expression by a wireless-powered optogenetic designer cell implant

“Mammalian synthetic biology has significantly advanced the design of gene switches that are responsive to traceless cues such as light, gas and radio waves, complex gene circuits, including oscillators, cancer-killing gene classifiers and programmable biocomputers, as well as prosthetic gene networks that provide treatment strategies for gouty arthritis, diabetes and obesity. Akin to synthetic biology promoting prosthetic gene networks for the treatment of metabolic disorders, cybernetics advances the design of functional man–machine interfaces in which brain–computer interfaces (BCI) process brain waves to control electromechanical prostheses, such as bionic extremities and even wheel chairs. The advent of synthetic optogenetic devices that use power-controlled, light-adjustable therapeutic interventions18 will enable the merging of synthetic biology with cybernetics to allow brain waves to remotely control the transgene expression and cellular behaviour in a wireless manner.”


Anthropology, Biology, Biometrics, Brain, Education, History, Medicine, Neural Networks, Optics, PDF, Science

The Optics of Ibn Al-Haytham, Books I–III: On Direct Vision (c1028-38)

“This is the first English translation of first three out of the 7 volumes of the fundamental work on optics by the medieval Arab scientist Ibn al-Haitham or Alhazen (965–c1039). His book exerted a great influence upon science through Vitelo, Roger Bacon, Peckham and Kepler. Alhazen investigated many particular cases of reflection and refraction, and drew attention to the light-ray’s property of retracing its path when reversed. He was the first to give a detailed description of the human eye and to study binocular vision. Certain ophthalmological terms originated from the Latin translation of Alhazen’s Arabic text, e.g. retina and cornea. The Book of Optics (Kitāb al-Manāẓir, كتاب المناظر) presented experimentally founded arguments against the widely held extramission theory of vision (as held by Euclid in his Optica) and in favour of intromission theory, as supported by thinkers such as Aristotle, the now accepted model that vision takes place by light entering the eye.”


Art, Biology, Biometrics, Brain, Education, Mind, Psychology, Science, Society

Secrets of the Creative Brain

“Part of what comes with seeing connections no one else sees is that not all of these connections actually exist. “Everybody has crazy things they want to try,” that same subject told me. “Part of creativity is picking the little bubbles that come up to your conscious mind, and picking which one to let grow and which one to give access to more of your mind, and then have that translate into action.””


AI, Algorithm, Biometrics, Brain, Capitalism, Cybernetics, Economy, Education, Emergence, Ethics, Man/Machine, Robots, Science, Social intelligence, Society

Will You Lose Your Job To a Robot?

“The biggest exception will be jobs that depend upon empathy as a core capacity — schoolteacher, personal service worker, nurse. These jobs are often those traditionally performed by women. One of the bigger social questions of the mid-late 2020s will be the role of men in this world.” — Jamais Cascio, technology writer and futurist


Algorithm, Analog Computing, Brain, Code, Cybernetics, Download, History, Interface, Logic, Mathematics, Memory

From Memex to Hypertext: Vannevar Bush and the Mind’s Machine (1991)

“Vannevar Bush, the engineer who designed the world’s most powerful analog computer, envisioned the development of a new kind of computing machine he called Memex. For many computer and information scientists, Bush’s Memex has been the prototype for a machine to help people think. This volume, which the editors have divided into sections on the creation, extension, and legacy of the Memex, combines seven essays by Bush with eleven others by others that set his ideas within a variety of contexts. The essays by Bush range chronologically from the early “The Inscrutable Thirties” (1933), “Memorandum Regarding Memex” (1941), and “As We May Think” (1945), to “Memex II” (1959), “Science Pauses” (1967), “Memex Revisited” (1967), and a passage from “Of Inventions and Inventors” (1970). Bush’s essays are surrounded by four chapters that place his changing plans for the Memex within his career and within information technology before digital computing. The contributors include Larry Owens, Colin Burke, Douglas C. Engelbart, Theodor H. Nelson, Linda C. Smith, Norman Meyrowitz, Tim Oren, Gregory Crane, and Randall H. Trigg.”

Memex animation


AI, Animals, Brain, Emergence, Ethics, philosophy, Religion, Robots, Science, Society

Buddhist perspectives on AI

“From the viewpoint of Buddhism, all life is emergent, entities functioning at a capacity greater than the sum of their parts. There is no special qualifier that separates any form of intelligence from another (note that even consciousness is on the list of things that we aren’t.”. This means that an intelligence inside of a robot body, a computer, or existing on the Internet would be just as worthy of being considered “alive” as a squirrel, a human, or a bacteria. Further, Buddhism accepts the existence of life that does not have a physical body. In the Buddhist mythology, beings that exist in realms without physical bodies are described and treated the same as those with physical bodies. Although this ethic is ascribed to mythical beings, if we begin to see actual beings that exist in “formless realms”, most Buddhists would likely see no problem accepting them as living. In Buddhism, a computer intelligence would be viewed by most as a new form of life, but one equally possessed of the heaps and equally capable of emergent behavior and enlightenment. The Dalai Lama, Thich Nhat Hanh, and several other high profile Buddhist thinkers have already spoken in support of AI as a living being.”


Anthropology, Art, Biological Computation, Biology, Biometrics, Brain, Deep Learning, Music, Neural Networks, Psychology, Science, Social intelligence, Society, Sound

The Neuroscience of Improvisation

Charles Limb has been investigating rap. “It’s what kids are doing spontaneously when growing up… and improvisation is a strong theme. It incorporates language and rhythmic music very equally.” Limb has been scanning the brains of rappers the same way he looked at jazz musicians: comparing fMRIs when they recited memorized passages to when they “freestyled,” or improvised in rhyme. Although the study is still in progress, preliminary data suggest “major changes in brain activity when you go from memorized rap to freestyle.” Can studies of improvisation unlock more general secrets of creativity? Limb hopes to do similar investigations of artists as they draw or paint. The moderator ended with an inevitable question about art and science: “It is worth the effort to measure and quantify something abstract and artistic… to demystify what we enjoy the mystery of?” Limb saw nothing “threatening or reductionist” in the work of neuroscientists. “Humans are hardwired to seek art, and there are very few things that engage the brain on the level that music does. To understand the neural basis of creativity teaches us something fundamental about who we are, why we’re here.” Improvisation “shows us what the mind can do,” Marcus added. “The ability of human beings to improvise tells us a lot about the ultimate scope of our capabilities.”