“Mammalian synthetic biology has significantly advanced the design of gene switches that are responsive to traceless cues such as light, gas and radio waves, complex gene circuits, including oscillators, cancer-killing gene classifiers and programmable biocomputers, as well as prosthetic gene networks that provide treatment strategies for gouty arthritis, diabetes and obesity. Akin to synthetic biology promoting prosthetic gene networks for the treatment of metabolic disorders, cybernetics advances the design of functional man–machine interfaces in which brain–computer interfaces (BCI) process brain waves to control electromechanical prostheses, such as bionic extremities and even wheel chairs. The advent of synthetic optogenetic devices that use power-controlled, light-adjustable therapeutic interventions18 will enable the merging of synthetic biology with cybernetics to allow brain waves to remotely control the transgene expression and cellular behaviour in a wireless manner.”
“Under the impression of today’s global crisis and the rise of ecological thinking, confronted with smart, ubiquitous technosystems and the impression of interconnectedness, there appears a new urge to excavate the remnants of the past. The articles of this issue suggest that in order to understand present technologies, we need to account the systems thinking that fostered their emergence, and that we cannot gain insight into the afterlives of systems without exploring their technologies.
The nine contributions ask how these debates and affective states survive and live on in today’s discussions of media ecologies, environmentalism, object-oriented philosophies, computer simulations, performative art, and communication technologies. In this sense, they take the renaissance of systems thinking in the late 20th and early 21st Century as an effect of various system crisis and explore new media technologies as stabilizing ‘cures’ against the dystopian future scenarios that emerged after World War II. The articles of this issue suggest that in order to understand present technologies, we need to account the systems thinking that fostered their emergence, and that we cannot gain insight into the afterlives of systems without exploring their technologies.”
Charles Limb has been investigating rap. “It’s what kids are doing spontaneously when growing up… and improvisation is a strong theme. It incorporates language and rhythmic music very equally.” Limb has been scanning the brains of rappers the same way he looked at jazz musicians: comparing fMRIs when they recited memorized passages to when they “freestyled,” or improvised in rhyme. Although the study is still in progress, preliminary data suggest “major changes in brain activity when you go from memorized rap to freestyle.” Can studies of improvisation unlock more general secrets of creativity? Limb hopes to do similar investigations of artists as they draw or paint. The moderator ended with an inevitable question about art and science: “It is worth the effort to measure and quantify something abstract and artistic… to demystify what we enjoy the mystery of?” Limb saw nothing “threatening or reductionist” in the work of neuroscientists. “Humans are hardwired to seek art, and there are very few things that engage the brain on the level that music does. To understand the neural basis of creativity teaches us something fundamental about who we are, why we’re here.” Improvisation “shows us what the mind can do,” Marcus added. “The ability of human beings to improvise tells us a lot about the ultimate scope of our capabilities.”
“The book examines Kant’s influence on five strands of nineteenth-century scientific thought: Naturphilosophie and the effect of German Romanticism (especially Goethe) on biology; Fries’s philosophy of science; Helmholtz’s rejection of Naturphilosophie and Romanticism; neo-Kantianism and its return to “methodological” concerns in natural science and academic philosophy; and Poincaré and his reflections on scientific epistemology. The essays give a nuanced picture of Kant’s legacy to nineteenth-century thinkers and of the rich interaction between philosophical ideas and discoveries in the natural and mathematical sciences during this period. They point to the ways that the scientific developments of the nineteenth century link Kant’s thought to the science of the twentieth century.”
“There has been considerable interest in bacterial communities wherein a bacterium is connected to neighbor- ing bacteria by means of narrow nanowires. It is believed that the purpose of the nanowires is to allow for intercellular electronic communications. More advanced on the evolutionary scale are the more modern bacterial communities which are wireless. The electromagnetic signals sent from a bacterium to neighboring bacteria can be due to relatively low frequency electron level transitions within DNA.”
“New research suggests that microbial life can be even richer: highly social, intricately networked, and teeming with interactions . Bassler  and other researchers have determined that bacteria communicate using molecules comparable to pheromones. By tapping into this cell-to-cell network, microbes are able to collectively track changes in their environment, conspire with their own species, build mutually beneficial alliances with other types of bacteria, gain advantages over competitors, and communicate with their hosts – the sort of collective strategizing typically ascribed to bees, ants, and people, not to bacteria. Eshel Ben-Jacob  indicate that bacteria have developed intricate communication capabilities (e.g. quorum-sensing, chemotactic signalling and plasmid exchange) to cooperatively self-organize into highly structured colonies with elevated environmental adaptability, proposing that they maintain linguistic communication. Meaning-based communication permits colonial identity, intentional behavior (e.g. pheromone-based courtship for mating), purposeful alteration of colony structure (e.g. formation of fruiting bodies), decision-making (e.g. to sporulate) and the recognition and identification of other colonies – features we might begin to associate with a bacterial social intelligence.”